About this course
This course covers all the scientific foundations needed to understand how Chimeric Antigen Receptor (CAR) T cells are engineered, their mechanism of action, the main challenges associated with CAR T cell therapies and the promises they hold for tomorrow's curative medicine.
This course also includes a first-in-class resource: Biotech Toolboxes. Biotech toolboxes offer different complementary ways to use relevant key terms, essential for mastering the common territory of all biotechnology. These terms constitute a growing Biotech Toolboxes Encyclopedia, a framework for the creation of shareable life sciences knowledge for all stakeholders in healthcare.
- All professionals involved in oncology drug development.
- All biomedical professionals in need of continuing medical education.
- Investors and other enablers of oncology drug pipelines.
- Regulatory affairs and regulatory science professionals.
- Cancer care providers and caregivers that are non-oncologists.
- University students interested in life sciences.
- Anyone with a strong interest in cancer therapies.
By the end of the course, you will have a clear conceptual understanding of:
- immunological cytotoxicity;
- the main classes of cytotoxic immune system cells;
- the notion of cancer immunosurveillance;
- MHC 1, T cell receptors and T cell cytotoxicity.
In addition, you will learn:
- how CAR T cells are engineered;
- how CAR T cell therapy is administered;
- what side effects it may have and how are these side effects managed;
- what are the limitations of current CAR T cell therapies;
- what may be future CAR T cell therapies and what diseases they may address.
- Unit 1 - Introduction
- Unit 2 - The Killer Cells within us
- Unit 3 - Immunosurveillance
- Unit 4 - The making of Serial Killers
- Unit 5 - The Kymriah Protocol
- Unit 6 - Side Effects
- Unit 7 - The Fantastic Voyages of the Future
Prior knowledge of basic cell biology and fundamentals of cancer biology recommended, but not required.
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