Jean-Michel Molina, Jens Lundgren , Fiona Mulcahy, Prof Jean-Michel Molina, Dr laurent COTTE, Dr Ann Sullivan, Prof Jeffrey Lazarus, Prof Gilles Pialoux, Dr Bea Vuylsteke, Dr Thijs Reyniers, Prof Sheena McCormack, and MItzy Gafos

HIV: Pre-exposure Prophylaxis - PrEP

  • MOOC
  • Self-Paced
  • English
  • Medicine

About this course

Major advances have been achieved in the treatment of HIV infection but the number of new HIV-infections remains high worldwide, around 2.1 million in 2015 according to the latest UNAIDS report. Data strongly support the need to strengthen HIV prevention and to implement new effective prevention methods. Pre-exposure prophylaxis, PrEP has in several studies been proven to prevent sexual transmission of HIV infection. This course offers an introduction to the principles of PrEP and clinical considerations related to PrEP e.g. prescription, monitoring and adherence. In 2016 PrEP was approved by the European Commision and will in the years to come be implemented in Europe. This course provides information of how to engage community and key stakeholders for the implementation of PrEP and what impact PrEP could have on the HIV epidemic. The course also include examples of how PrEP was implemented in France and the UK.

Who is this course for?

Clinicians. Especially clinicians from HIV high-incidence countries in the European Region, predominantly Eastern Europe and Central Asia.

What will I learn?

By the end of this course, students will be able to:

  • Explain the principles of pre-exposure prophylaxis PrEP for HIV prevention.

  • Describe the main data with oral PrEP from trials in men and women.

  • Be able to prescribe and monitor PrEP as part of a combination harm reduction package.

  • Be able to advocate for implementation of PrEP in national programmes.

What do I need to know?

Participants should have a basic background in medicine.

Course Structure

The course consists of 4 chapters:

Chapter 1: Introduction to the course

Chapter 2: Basic information on PrEP
In this chapter you will be introduced to the principles of PrEP and the current studies supporting the use of oral PrEP.

Chapter 3: Clinical considerations in relation to PrEP.
In this chapter you will learn how to define key populations for PrEP and how to prescribe and monitor PrEP in patients. Furthermore you will learn how you can ensure adherence to PrEP, how to assess overall risk for STIs and finally how to manage seroconversion in a person on PrEP.

Chapter 4: Implementation of PrEP
In this chapter you will be presented to how PrEP was implemented in France and the United Kingdom. You will learn how to engage community and key stakeholders for implementation of PrEP. Finally you will learn how PrEP can impact the HIV epidemic.

Study time for those who will participate in the exam (= upgraded to the Certificate of Accomplishment)